CTBP1/BARS

Protein Data Bank ID: 4LCE
Protein Name:  C-terminal-binding protein 1 (CTBP1)/
Refeldin A (BFA)-induced ADP-ribosylated substrate (BARS)
Organism: Homo sapiens
Title of Drawing: “Snow leopards”

This drawing was initiated by a good friend who is working on the BARS protein and is enthusiastic about small and big cats. As in the Russian language the snow leopard is often termed “(snow) bars”, the protein structure inevitably resulted in this feline couple.
BARS is a multifunctional protein. In the nucleus, it can bind a specific DNA region and thereby regulate the transition from epithelial to mesenchymal type of tissue. In the cytosol, it plays a role in membrane fission, including fragmentation of the Golgi apparatus.